Mani Raman, BSc, BScH, MSc, MD, FRCPC, DABD

The Centre for Dermatology
312 Highway 7 East
Richmond Hill, Ontario, Canada
L4B 1A5
905-889-2003

 

Specialty: Dermatology

 

Dr. Norman R. Wasel, Dermatologist Specialist in Psoriasis

Research Interests: Acne, Crow's Feet, Glabellar Lines, Psoriasis, Onychomycosis, Rosacea


Dr. Mani Raman is a board certified Dermatologist who has been practicing dermatology since 1999. Dr. Raman has many years of clinical research experience as a Principal Investigator participating in over 16 trials since 2003. He has conducted Phase II-IV trials for many dermatologic conditions and diseases including, psoriasis, crow's feet, onychomycosis, and acne.

Dr. Raman is a member of numerous associations including the American Society for Dermatologic Surgery, Canadian Dermatology Association, Royal College of Physicians and Surgeons of Canada, and the Toronto Dermatological Society.

 

Click to view Dr. Mani Raman's Publications

Papp KA, Gooderham MJ, Girard G, Raman M, Strout V. Phase I randomized study of KHK4083, an anti-OX40 monoclonal antibody, in patients with mild to moderate plaque psoriasis. J Eur Acad Dermatol Venereol 2017 Aug; 31(8): 1324-32. Epub 2017 Jun 14. PMID: 28556418 / doi: 10.1111/jdv.14313

Simpson EL, Bieber T, Guttman-Yassky E, Beck LA, Blauvelt A, Cork MJ, Silverberg JI, Deleuran M, Kataoka Y, Lacour JP, Kingo K, Worm M, Poulin Y, Wollenberg A, Soo Y, Graham NM, Pirozzi G, Akinlade B, Staudinger H, Mastey V, Eckert L, Gadkari A, Stahl N, Yancopoulos GD, Ardeleanu M; SOLO 1 and SOLO 2 Investigators. Two phase 3 trials of dupilumab versus placebo in atopic dermatitis. N Engl J Med 2016 Dec 15; 375(24): 2335-48. Epub 2016 Sep 30. PMID: 27690741

Bissonnette R, Papp KA, Poulin Y, Gooderham M, Raman M, Mallbris L, Wang C, Purohit V, Mamolo C, Papacharalambous J, Ports WC. Topical tofacitinib for atopic dermatitis: a phase IIa randomized trial. Br J Dermatol 2016 Nov; 175(5): 902-911. Epub 2016 Sep 24. PMID: 27423107 / doi: 10.1111/bjd.14871

Gordon KB, Blauvelt A, Papp KA, Langley RG, Luger T, Ohtsuki M, Reich K, Amato D, Ball SG, Braun DK, Cameron GS, Erickson J, Konrad RJ, Muram TM, Nickoloff BJ, Osuntokun OO, Secrest RJ, Zhao F, Mallbris L, Leonardi CL; UNCOVER-1 Study Group; UNCOVER-2 Study Group; UNCOVER-3 Study Group. Phase 3 trials of ixekizumab in moderate-to-severe plaque psoriasis. N Engl J Med 2016 Jul 28; 375(4): 345-56. Epub 2016 Jun 8. PMID: 27299809 / doi: 10.1056/NEJMoa1512711

Papp K, Menter MA, Raman M, Disch D, Schlichting DE, Gaich C, Macias W, Zhang X, Janes JM. A randomized phase 2b trial of baricitinib, an oral Janus kinase JAK1/JAK2 inhibitor, in patients with moderate-to-severe psoriasis. Br J Dermatol 2016 Jun; 174(6):1266-76. Epub 2016 Apr 5. PMID: 26800231 / doi: 10.1111/bjd.14403

Gupta AK, Sibbald RG, Andriessen A, Belley R, Boroditsky A, Botros M, Chelin R, Gulliver W, Keast D, Raman M. Toenail onychomycosis – a Canadian approach with a new transungual treatment: development of a clinical pathway. J Cutan Med Surg 2015 Sep-Oct; 19(5):440-9. Epub 2015 Apr 9. PMID: 25857439 / doi: 10.1177/1203475415581310

Griffiths CE, Reich K, Lebwohl M, van de Kerkhof P, Paul C, Menter A, Cameron GS, Erickson J, Zhang L, Secrest RJ, Ball S, Braun DK, Osuntokun OO, Heffernan MP, Nickoloff BJ, Papp K; UNCOVER-2 and UNCOVER-3 investigators. Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials. Lancet 2015 Aug 8; 386(9993):541-51. Epub 2015 Jun 10. PMID: 26072109 / doi: 10.1016/S0140-6736(15)60125-8

Tan J, Humphrey S, Vender R, Barankin B, Gooderham M, Kerrouche N, Audibert F, Lynde C; POWER study group. A treatment for severe nodular acne: a randomized investigator-blinded, controlled, noninferiority trial comparing fixed-dose adapalene/benzoyl peroxide plus doxycycline vs. oral isotretinoin. Br J Dermatol 2014 Dec; 171(6):1508-16. Epub 2014 Oct 28. PMID: 24934963 / doi: 10.1111/bjd.13191

Stein Gold L, Kircik L, Fowler J, Jackson JM, Tan J, Draelos Z, Fleischer A, Appell M, Steinhoff M, Lynde C, Sugarman J, Liu H, Jacovella J; Ivermectin Phase 3 Study Group. Long-term safety of ivermectin 1% cream vs azelaic acid 15% gel in treating inflammatory lesions of rosacea: results of two 40-week controlled, investigator-blinded trials. J Drugs Dermatol 2014 Nov; 13(11):1380-6. PMID: 25607706

Langley RG, Elewski BE, Lebwohl M, Reich K, Griffiths CE, Papp K, Puig L, Nakagawa H, Spelman L, Sigurgeirsson B, Rivas E, Tsai TF, Wasel N, Tyring S, Salko T, Hampele I, Notter M, Karpov A, Helou S, Papavassilis C; ERASURE Study Group; FIXTURE Study Group. Secukinumab in plaque psoriasis--results of two phase 3 trials. N Engl J Med 2014 Jul 24; 371(4):326-38. Epub 2014 Jul 9. PMID: 25007392 / doi: 10.1056/NEJMoa1314258

Raman M. Perforating disorders: summary notes. J Cutan Med Surg 2000; 4(1): 16-18; quiz 18, 25. PMID: 10689222

Raman M, Sibbald RG. The relationship of bacterial load on Apligraf primary takes for non healing venous leg ulcers. Canadian Association of Wound Care Syllabus 1998: 69. 

Sibbald RG, Raman M. The use of Apligraf and importance of overlap technique for primary graft taking in venous leg ulcers. Canadian Association of Wound Care Syllabus 1998: 69. 

Solish N, Raman M, Pollack SV. Approaches to acne scarring: a review. J Cutan Med Surg 1998; 2(Suppl 3): S3-24. PMID: 9873120 

Raman M, DeKoven J. Localized Hailey-Hailey disease of the penis. J Cutan Med Surg 1998; 3(): 17. 

Sibbald RG, Raman M. New approaches to wound healing. Using a human living skin equivalent: clinical perspectives. Therapeutic Advances In Dermatology 1998: 1-10. 

Raman M, Waitzer S, Rosen C. Malignant B-cell lymphoma in a patient with eosinophilic fasciitis. J Cutan Med Surg 1997; 2(Suppl 1): 13. 

Raman M, ElMaraghy A, Jain M, Sequeira K. Three Dimensional Computer Imaging. UTMJ 1993; 70(3): 28-31. 

Kawasaki A, Raman M, Yang L-Y, James L, Steiner G. The effect of chronic and acute hyperinsulinemia on VLDL secretion and ACAT activity. Proceedings of the Frontiers in Physiology and Pharmacology 1992. 

Raman M, Steiner G. The effect of insulin on VLDL metabolism. Proceedings of the Clinical Research Society of Toronto 1990; 33(90). 

Raman M, Steiner G. The use of radiolabelled tracers in order to assess the effect of chronic exogenous hyperinsulinemia on VLDL metabolism. Proceedings of the Frontiers in Physiology and Pharmacology 1990; 10: 35. 

Raman M, Steiner G. The effect of insulin on VLDL-triglyceride secretion and glucose production by the perfused rat liver. Diabetes 1990; 39 (Suppl. 1): 45A. 

Raman M, Radziuk J, Hetenyi G. Distribution and kinetics of glucose in rats analyzed by noncompartmental and compartmental analysis. Am J Physiol 1990; 259 (2 Part 1): E292-E303. 

Hetenyi G, Anderson PJ, Raman M, Ferrarotto C. Gluconeogenesis from glycine and serine in fasted normal and diabetic rats. Biochem J 1988; 253(1): 27-32. 

Raman M. Water project training - Indonesia. Project 3-P-81-0181 Completion Report for Water Supply and Sanitation Sector - Health Sciences Division. International Development Research Centre Report 1986. 

Raman M. Occupational injuries - Korea. Project 3-P-81-0210 Completion Report for Occupational Health and Environmental Toxicology Sector - Health Sciences Division. International Development Research Centre Report 1986. 

Raman M. Mobile Nursing Clinic - Philippines. Project 3-P-81-0232 Completion Report for Maternal and Child Health Care Sector - Health Sciences Division. International Development Research Centre Report 1986. 

Raman M. Initiation of sperm mobility (Phase II) - Thailand. Project 3-P-82-0008 Completion Report for Tropical and Infectious Disease Sector - Health Sciences Division. International Development Research Centre Report 1986. 

Raman M. Sexually transmitted diseases - Thailand. Project 3-P-82-0035 Completion Report for Tropical and Infectious Diseases Sector - Health Sciences Division. International Development Research Centre Report 1986. 

Raman M. Rural sanitation - Sierra Leone. Project 3-P-82-0054 Completion Report for Water Supply and Sanitation Sector - Health Sciences Division. International Development Research Centre Report 1986. 

Raman M. Diarrhoeal diseases program (Phase II) - Global. Project 3-P-82-0159 Completion Report for Tropical and Infectious Diseases Sector - Health Sciences Division. International Development Research Centre Report 1986. 

Raman M. Bio-control of mosquitoes (Phase II) - New Caledonia. Project 3-P-82-1008 Completion Report for Tropical and Infectious Diseases Sector - Health Sciences Division. International Development Research Centre Report 1986. 

Raman M. Bacterial growth in infant formula - Chile. Project 3-P-83-0003 Completion Report for Maternal and Child Health Care Sector - Health Sciences Division. International Development Research Centre Report 1986. 

Raman M. Pharmaceutical distribution - Nepal. Project 3-P-83-0004 Completion Report for Health Services Research Sector - Health Sciences Division. International Development Research Centre Report 1986. 

Raman M. Pneumoconiosis - Korea. Project 3-P-83-0136 Completion Report for Occupational Health and Environmental Toxicology Sector - Health Sciences Division. International Development Research Centre Report 1986. 

Raman M. Gastric cancer - Korea. Project 3-P-83-0144 Completion Report for Occupational Health and Environmental Toxicology Sector - Health Sciences Division. International Development Research Centre Report 1986. 

Raman M. The prolactin response to suckling with and without the Oxford Thin Latex Nipple Shield - Thailand. Project 3-P-83-0188 Completion Report for Maternal and Child Health Care Sector - Health Sciences Division. International Development Research Centre Report 1986. 

Raman M. Tropical disease research (Phase IV) - Glo­bal. Project 3-P-80-0168 Completion Report for Tropical and Infectious Diseases Sector - Health Sciences Division. International Development Research Centre Report 1985. 

Raman M. Tropical disease research (Phase V) - Global. Project 3-P-83-0147 Completion Report for Tropical and Infectious Diseases Sector - Health Sciences Division. International Development Research Centre Report 1985. 

Raman M. Bilharzia (Phase II) - Egypt. Project 3?P?80?0194 Completion Report for Tropical and Infectious Diseases Sector - Health Sciences Division. International Development Research Centre Report 1985. 

Raman M. Time-temperature indicators (Phase II) - Global. Project 3?P?81?0023?02 Completion Report for Rural Health Care Delivery Sector - Health Sciences Division. International Development Research Centre Report 1985. 

Raman M. Chancroid - Kenya. Project 3?P?81?0041 Completion Report for Tropical and Infectious Diseases Sector - Health Sciences Division. International Development Research Centre Report 1985. 

Raman M. Epidemiology of diarrhea - Egypt. Project 3?P?79?0076 Completion Report for Tropical and Infectious Diseases - Health Sciences Division. International Development Research Centre Report 1985. 

Raman M. Rainwater collection - Sierra Leone. Project 3?P?80?0091 Completion Report for Water Supply and Sanitation Sector - Health Sciences Division. International Development Research Centre Report 1985. 

Raman M. Syphilis - Zambia. Project 3?P?81?0094 Completion Report for Tropical and Infectious Diseases Sector - Health Sciences Division. International Development Research Centre Report 1985. 

Raman M. Piggery waste treatment (Phase II) - Singapore. Project 3?P?79?0071 Completion Report for Rural Water Supply and Sanitation Sector - Health Sciences Division. International Development Research Centre Report 1984. 

Raman M. Oral contraceptives/lactation - Indonesia. Project 3?P?79?0130 Completion Report for Maternal and Child Health Sector - Health Sciences Division. International Development Research Centre Report 1984. 

Raman M. Oral rehydration - Trinidad. Project 3?P?79?0165 Completion Report for Rural Health Care Delivery Sector - Health Sciences Division. International Development Research Centre Report 1984.

Raman M. Manpower training project - Global/Africa. Project 3?P?80?0023 Completion Report for Rural Water Supply and Sanitation Sector - Health Sciences Division. International Development Research Centre Report 1984. 

Raman M. Vasectomy/Arteriosclerosis - Canada. Project 3?P?80?0035 Completion Report for Fertility Regulation Methods Sector - Health Sciences Division. International Development Research Centre Report 1984.

Raman M. Gastroenteritis - Chile. Project 3?P?80?0083 Completion Report for Tropical and Infectious Diseases Sector - Health Sciences Division. International Development Research Centre Report 1984. 

Raman M. Water management - Ethiopia. Project 3?P?80?0088 Completion Report for Rural Water Supply and Sanitation Sector - Health Sciences Division. International Development Research Centre Report 1984. 

Raman M. Hemorrhagic fever - Argentina. Project 3-P-80-0133 Completion Report for Tropical and Infectious Diseases Sector - Health Sciences Division. International Development Research Centre Report 1984.

Raman M. Palm oil wastes - Malaysia. Project 3-P-78?0014 Completion Report for Rural Water Supply and Sanitation Sector - Health Sciences Division. International Development Research Centre Report 1983. 

Raman M. Water pumping technology - Malaysia. Project 3-P-78-0082 Completion Report for Rural Water Supply and Sanitation Sector - Health Sciences Division. International Development Research Centre Report 1983. 

Raman M. Contraceptive research - Global. Project 3-P-78-0096 Completion Report for Fertility Regulation Methods Sector - Health Sciences Division. International Development Research Centre Report 1983. 

Raman M. Waste management - Thailand. Project 3-P-78-0097 Completion Report for Rural Water Supply and Sanitation Sector - Health Sciences Division. International Development Research Centre Report 1983. 

Raman M. Tuberculosis - Kenya. Project 3-P-79-0028 Completion Report for Tropical and Infectious Diseases Sector - Health Sciences Division. International Development Research Centre Report 1983.

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